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Published Online: June 1953

THE DIAGNOSTIC USE OF AMOBARBITAL SODIUM ("AMYTAL SODIUM") IN BRAIN DISEASE

EDWIN A. WEINSTEIN, ROBERT L. KAHN, LEROY A. SUGARMAN, and LOUIS LINNAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 109, Number 12

https://doi.org/10.1176/ajp.109.12.889

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Abstract

The use of amobarbital sodium (amytal sodium ^R) as a diagnostic test for brain disease is described. In 57 of 88 patients with proven brain disease, who on clinical examination showed no disturbances in behavior, the intravenous administration of the drug produced patterns of disorientation for time, place, and person and denial of illness. These changes were not obtained in any of 50 control patients. The applicability of the procedure to the study of alterations in brain function caused by structural, iatrogenic, metabolic, and toxic agents is discussed.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 109 • Number 12 • June 1953

Pages: 889 - 894

PubMed: 13050814

History

Published in print: June 1953

Published online: 1 April 2006

Authors

Affiliations

EDWIN A. WEINSTEIN

The Neurological and Psychiatric Services of The Mount Sinai Hospital, New York.

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ROBERT L. KAHN

The Neurological and Psychiatric Services of The Mount Sinai Hospital, New York.

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LEROY A. SUGARMAN

The Neurological and Psychiatric Services of The Mount Sinai Hospital, New York.

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LOUIS LINN

The Neurological and Psychiatric Services of The Mount Sinai Hospital, New York.

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THE DIAGNOSTIC USE OF AMOBARBITAL SODIUM ("AMYTAL SODIUM") IN BRAIN DISEASE

Abstract

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