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Published Online: April 1954

MENTAL AND ELECTROENCEPHALOGRAPHIC CHANGES FOLLOWING INTRAVENOUS BARBITURATES IN ORGANIC DISEASE OF THE BRAIN

PHILIP S. BERGMAN, HANS H. STROO, and RHODA FEINSTEINAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 110, Number 10

https://doi.org/10.1176/ajp.110.10.770

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Abstract

1. Simultaneous comparisons were made between the mental state and the EEG changes induced by intravenous barbiturates in subjects with and without organic brain disease.

2. Normal subjects did not become disoriented following intravenous sodium amytal and the EEG effects were the same as those noted by others.

3. Although disorientation often followed the drug in subjects with structural lesions and normal records, the EEG changes were not different from those occurring in controls. In abnormal records, there was a reduction or disappearance of slow activity after the drug concomitant with the development of an organic mental syndrome.

4. Focal abnormalties were occasionally elicited, or, if previously present, accentuated by the drug.

5. Under the conditions of the experiment, the mental state did not parallel the state of the EEG. Possible reasons for this discrepancy are discussed.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 110 • Number 10 • April 1954

Pages: 770 - 773

PubMed: 13138756

History

Published in print: April 1954

Published online: 1 April 2006

Authors

Details

PHILIP S. BERGMAN

The Department of Neurology and Psychiatry, New York University College of Medicine, the Third Division of Neurology and Psychiatry, Bellevue Hospital, and the Department of Neurology, The Mount Sinai Hospital, New York.

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HANS H. STROO

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RHODA FEINSTEIN

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MENTAL AND ELECTROENCEPHALOGRAPHIC CHANGES FOLLOWING INTRAVENOUS BARBITURATES IN ORGANIC DISEASE OF THE BRAIN

Abstract

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