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Published Online: April 1956

CLINICAL AND ELECTROENCEPHALOGRAM INVESTIGATION ON LARGACTIL IN PSYCHOSIS (PRELIMINARY STUDY)

Publication: American Journal of Psychiatry

Abstract

1. Experimental investigations have been carried out with Largactil on chronic and acute mental patients.
2. The over-all improvement in chronic cases was 69% and in acute cases 60%.
3. However, the transitory effects in acute cases indicate that while Largactil is extremely valuable in chronic psychosis, in acute psychotic breakdowns, it has value only as a sedative.
4. Electroencephalogram investigations showed that Largactil markedly decreases the muscle artefacts, decreases the frequency, and increases the voltage, causing a mild progressive synchronization and, in epileptics, it lessens the convulsive threshold.
5. In spastics it decreases spasticity through intravenous route, as tested by electromyogram.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 788 - 794
PubMed: 13302482

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Published in print: April 1956
Published online: 1 April 2006

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