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Published Online: March 1960

EFFICACY OF DIVIDED AND SINGLE DOSE SCHEDULES IN INSULIN COMA THERAPY

ARNOLD G. BLUMBERG, PETER LADERMAN, and MAX FINKAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 116, Number 9

https://doi.org/10.1176/ajp.116.9.839

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Abstract

The coma produced with the divided insulin doses did not occur earlier and was not deeper than that produced by the single dose. The increased effort in divided dose schedules is justified neither by increased safety nor by increased depth or duration of the induced hypoglycemia.

There was no evidence that the initial dose of insulin sensitized the subject so that subsequent doses produced a greater hypoglycemic effect. The total hypoglycemic effect of divided doses appears to be less, if anything, than the effect of a single dose.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 116 • Number 9 • March 1960

Pages: 839 - 840

PubMed: 13801700

History

Published in print: March 1960

Published online: 1 April 2006

Authors

Details

ARNOLD G. BLUMBERG

The Departments of Internal Medicine and Experimental Psychiatry, Hillside Hospital, Glen Oaks, L. I., N. Y.

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PETER LADERMAN

The Departments of Internal Medicine and Experimental Psychiatry, Hillside Hospital, Glen Oaks, L. I., N. Y.

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MAX FINK

The Departments of Internal Medicine and Experimental Psychiatry, Hillside Hospital, Glen Oaks, L. I., N. Y.

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EFFICACY OF DIVIDED AND SINGLE DOSE SCHEDULES IN INSULIN COMA THERAPY

Abstract

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