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Published Online: March 1961

THIORIDAZINE HYDROCHLORIDE IN THE TREATMENT OF BEHAVIOR DISORDERS IN EPILEPTICS

PABLO M. PAUIG, MARIE A. DELUCA, and ROGER G. OSTERHELDAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 117, Number 9

https://doi.org/10.1176/ajp.117.9.832

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Abstract

Mellaril was evaluated as treatment of behavior disorders in 100 epileptic patients in a study extending over a period of 3 to 10 months. Marked improvement in behavior was achieved in 61 patients and moderate improvement in another 28 patients.

An unexpected consequence was the concomitant reduction in epileptic seizures, 64 of the 100 patients exhibiting no or fewer convulsive attacks during the administration of Mellaril. This provides tacit evidence that control of the emotional factors can exert a beneficial effect on seizures. However, it is emphasized that specific anticonvulsant medication was continued throughout the course of this study.

Repeat examinations failed to reveal any signs of jaundice, photosensitivity, blood dyscrasia, extrapyramidal stimulation, or dermatitis.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 117 • Number 9 • March 1961

Pages: 832 - 833

PubMed: 13733416

History

Published in print: March 1961

Published online: 1 April 2006

Authors

Details

PABLO M. PAUIG

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MARIE A. DELUCA

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ROGER G. OSTERHELD

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Staff Psychiatrist, Monson State Hospital, Palmer, Mass.

Clinical Director, Monson State Hospital, Palmer, Mass.

Superintendent, Monson State Hospital, Palmer, Mass.

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THIORIDAZINE HYDROCHLORIDE IN THE TREATMENT OF BEHAVIOR DISORDERS IN EPILEPTICS

Abstract

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