COMPARISON OF BUTYRYLPERAZINE AND TRLFLUOPERAZINE IN CHRONIC SCHIZOPHRENIC SUBJECTS

WILLIAM MANDEL and PHILIP EVANSAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 119, Number 1

https://doi.org/10.1176/ajp.119.1.70

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Abstract

Butyrylperazine, a new phenothiazine of the piperazine series, was compared with trifluoperazine in a 3-month study involving 44 chronic schizophrenic patients. The study employed a double-blind, cross over design using a fixed dosage regimen of both drugs. A 2-week placebo interval was used prior to the cross over and at the completion of the study.

There were no significant differences in therapeutic effectiveness or incidence of side reactions between the drugs. Similarities between the drugs were greater than differences.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 119 • Number 1 • July 1962

Pages: 70 - 71

PubMed: 14469191

History

Published in print: July 1962

Published online: 1 April 2006

Authors

Details

WILLIAM MANDEL

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PHILIP EVANS

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Chief of Research, Napa State Hospital, Napa, Calif.

Staff Psychiatrist, Napa State Hospital, Napa, Calif.

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COMPARISON OF BUTYRYLPERAZINE AND TRLFLUOPERAZINE IN CHRONIC SCHIZOPHRENIC SUBJECTS

Abstract

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