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Published Online: November 1967

An Early Clinical Evaluation of Clopenthixol in Treatment-Resistant Female Schizophrenic Patients

ARTHUR WOLPERT, CHARLES SHEPPARD, and SIDNEY MERLISAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 124, Number 5

https://doi.org/10.1176/ajp.124.5.702

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Abstract

Some published results from the European literature regarding the therapeutic and untoward effects of clopenthixol therapy were replicated. Therapeutic response was demonstrated at a daily dosage of 50 mg. An initial drowsiness was noted within a few days of therapy. No laboratory abnormalities were noted.

The global impressions of the ward physician were confirmed by the statistical evaluation of the rating data. A significant improvement was demonstrated in this sample of treatment-resistant, chronic female schizophrenics. This has encouraged us to formulate a further, more extensive investigation of clopenthixol in a larger double-blind comparative study.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 124 • Number 5 • November 1967

Pages: 702 - 705

PubMed: 4860763

History

Published in print: November 1967

Published online: 1 April 2006

Authors

Affiliations

ARTHUR WOLPERT

Research Division, Central Islip State Hospital, Central Islip, N. Y. 11722

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CHARLES SHEPPARD

Research Division, Central Islip State Hospital, Central Islip, N. Y. 11722

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SIDNEY MERLIS

Research Division, Central Islip State Hospital, Central Islip, N. Y. 11722

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An Early Clinical Evaluation of Clopenthixol in Treatment-Resistant Female Schizophrenic Patients

Abstract

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