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Published Online: December 1968

Diagnosis and Treatment of Drug Dependence of the Barbiturate Type

Publication: American Journal of Psychiatry

Abstract

The basic principles in treatment of patients suspected of, or known to be, physically dependent on barbiturates, nonbarbiturate sedatives, and/or "minor tranquilizers" are: stabilization on pentobarbital in daily amounts and frequency of dosage sufficient to completely suppress barbiturate-type abstinence phenomena and produce minimal signs of barbiturate intoxication; and progressive reduction of pentobarbital dosage at the rate of not more than 100 mg. a day after three to five days of stabilization.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 758 - 765
PubMed: 5698445

History

Published in print: December 1968
Published online: 1 April 2006

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ABRAHAM WIKLER
Professor of psychiatry and pharmacology, department of psychiatry, University of Kentucky College of Medicine and University Hospital, Lexington, Ky. 40506

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