Effectiveness of Lithium Carbonate in the Treatment of Manic-Depressive Illness

CHRISTIAAN D. VAN DER VELDEAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 127, Number 3

https://doi.org/10.1176/ajp.127.3.345

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Abstract

The author reports on the responses to lithium cabonate of 75 manic-depressive patients. Lithium carbonate was found to be highly effective in the acute manic state but without merit in the treatment of acute depression. Its efficacy was inversely related to age. Response to the drug varied in some patients; a positive response at one time was no guarantee for a similar response in subsequent trials. The possibility of different biochemical states underlying similar clinical states is discussed.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 127 • Number 3 • September 1970

Pages: 345 - 351

PubMed: 5458599

History

Published in print: September 1970

Published online: 1 April 2006

Authors

Affiliations

CHRISTIAAN D. VAN DER VELDE

Research psychiatrist at the Abraham Ribicoff Research Center, Norwich Hospital, Norwich, Conn. 06360

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Effectiveness of Lithium Carbonate in the Treatment of Manic-Depressive Illness

Abstract

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