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Published Online: March 1971

Tranylcypromine-Trifluoperazine Combination in the Treatment of Schizophrenia

DAVID L. HEDBERG, JOHN H. HOUCK, and BERNARD C. GLUECK, JR.Authors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 127, Number 9

https://doi.org/10.1176/ajp.127.9.1141

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Abstract

Ninety-six schizophrenic patients participated in a double-blind, crossover study of the efficacy of trifluoperazine and tranylcypromine therapy alone and in combination. Pseudoneurotic patients had a statistically significant response to tranylcypromine; paranoid (chronic undifferentiated) patients responded best to the combination therapy. The authors urge the use of computer-derived profiles of patients' symptom clusters rather than their diagnoses to ensure selection of the optimum drug therapy.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 127 • Number 9 • March 1971

Pages: 1141 - 1146

PubMed: 4925299

History

Published in print: March 1971

Published online: 1 April 2006

Authors

Affiliations

DAVID L. HEDBERG

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JOHN H. HOUCK

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BERNARD C. GLUECK, JR.

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Research Psychiatrist, Institute of Living, 200 Retreat Ave., Hartford, Conn. 06103

Medical Director, Institute of Living, 200 Retreat Ave., Hartford, Conn. 06103

Director of Research, Institute of Living, 200 Retreat Ave., Hartford, Conn. 06103

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Tranylcypromine-Trifluoperazine Combination in the Treatment of Schizophrenia

Abstract

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