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Published Online: May 1972

Reduced Monoamine Oxidase Activity in Blood Platelets from Bipolar Depressed Patients

Publication: American Journal of Psychiatry

Abstract

Cellular monoamine oxidase (MAO) activity measured in blood platelets is significantly (45 percent) lower in depressed patients with a history of mania (bipolar patients) than in nonbipolar depressed patients and normal controls of similar age and sex. This difference in MAO activity may be related to other biological and psychological characteristics of these patients that suggest that bipolar patients constitute a specific subgroup among patients with affective disorders.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 1351 - 1357
PubMed: 5020182

History

Published in print: May 1972
Published online: 1 April 2006

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Chief, Clinical Research Unit, Section on Psychiatry, Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, Md.
Intern at Albert Einstein Hospital, Philadelphia, Pa.

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