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Published Online: May 1972

Effects of Imipramine and Dextroamphetamine on Behavior of Neuropsychiatrically Impaired Children

BERTRAND G. WINSBERG, IRV BIALER, SAMUEL KUPIETZ, and JACK TOBIASAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 128, Number 11

https://doi.org/10.1176/ajp.128.11.1425

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Abstract

This study assessed the comparative effectiveness of imipramine, placebo, and dextroamphetamine as therapeutic agents for the control of hyperkinetic and aggressive behaviors in children. Behavioral change under the drug conditions was evaluated using a 39-item behavior rating scale. The results indicate that imipramine is an effective agent for the control of hyperactivity and aggression in behaviorally impaired children. Implications of the findings for clinical application in pediatric psychopharmacology are presented and discussed.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 128 • Number 11 • May 1972

Pages: 1425 - 1431

PubMed: 4553490

History

Published in print: May 1972

Published online: 1 April 2006

Authors

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BERTRAND G. WINSBERG

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IRV BIALER

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SAMUEL KUPIETZ

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JACK TOBIAS

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Research Medical Director, Child Psychiatric Evaluation Research Unit, New York State Department of Mental Hygiene, 524 Clarkson Ave., Brooklyn, N.Y. 11203

Principal Research Scientist, Child Psychiatric Evaluation Research Unit, New York State Department of Mental Hygiene, 524 Clarkson Ave., Brooklyn, N.Y. 11203

Senior Research Scientist, Child Psychiatric Evaluation Research Unit, New York State Department of Mental Hygiene, 524 Clarkson Ave., Brooklyn, N.Y. 11203

Associate Professor, Department of Child Psychiatry, Downstate Medical Center, Brooklyn, N.Y.

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Effects of Imipramine and Dextroamphetamine on Behavior of Neuropsychiatrically Impaired Children

Abstract

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