High-Dose Cyclazocine Therapy of Opiate Dependence

RICHARD RESNICK, MAX FINK, and ALFRED M. FREEDMANAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 131, Number 5

https://doi.org/10.1176/ajp.131.5.595

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Abstract

Twenty-three former heroin addicts who had been stabilized on 4 to 5 mg. of cyclazocine per day had their dossage increased to 10 to 30 mg. per day. These increases resulted in mild, transient side effects. The narcotic-blocking activity of cyclazocine was extended to 48 hours by a daily dose of 10 mg. and to 72 hours by 20 mg. A daily dose of 3O mg. increased its blocking activity at 48 hours but not at 72 hours.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 131 • Number 5 • May 1974

Pages: 595 - 597

PubMed: 4594561

History

Published in print: May 1974

Published online: 9 March 2015

Authors

Details

RICHARD RESNICK

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MAX FINK

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ALFRED M. FREEDMAN

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Assistant Professor and Director, Division of Drug Abuse Research and Treatment, Department of Psychiatry, New York Medical College, Flower and Fifth Avenue Hospitals, 5 East 102nd St., New York, N.Y. 10029

Professor and Chairman, Department of Psychiatry, New York Medical College, Flower and Fifth Avenue Hospitals, 5 East 102nd St., New York, N.Y. 10029

Professor of Psychiatry, Health Sciences Center, State University of New York at Stony Brook

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High-Dose Cyclazocine Therapy of Opiate Dependence

Abstract

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