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Published Online: January 1936

HEMATOPORPHYRIN TREATMENT OF SEVERE DEPRESSIONS

D. Louis SteinbergAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 92, Number 4

https://doi.org/10.1176/ajp.92.4.901

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Abstract

1. Reports in the literature of the use of hematoporphyrin in the depressed psychoses were for the most part favorable.

2. There are by no means clear theories as to the physiological action of the drug.

3. Experiments with laboratory animals indicated a definite influence on the weight and an increased response to stimuli.

4. Laboratory studies had shown a tendency of the drug to elevate the blood count and to reduce the calcium level.

5. Fourteen patients in all were treated adequately with hematoporphyrin.

6. Two patients responded well, one of whom relapsed after a period of six weeks. The other continued to adjust on a low level.

7. Laboratory examinations failed to disclose any specific influence on the blood picture except a tendency to lowered cholesterol levels.

8. Our results do not warrant the use of this therapy in preference to any of the old armamentarium used in the treatment of depressed psychoses.

9. The use of this drug did not produce any deleterious toxic reaction.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 92 • Number 4 • January 1936

Pages: 901 - 913

History

Published in print: January 1936

Published online: 1 April 2006

Authors

Details

D. Louis Steinberg

Elgin, Ill.

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HEMATOPORPHYRIN TREATMENT OF SEVERE DEPRESSIONS

Abstract

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