Genome-Wide Pharmacogenetics of Antidepressant Response in the GENDEP Project

Received July 4, 2009; revision received Sept. 24, 2009; accepted Oct. 22, 2009. From the Medical Research Council Social, Genetic, and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London; the Laboratory of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, Poznan, Poland; the Croatian Institute for Brain Research, University of Zagreb Medical School, Zagreb, Croatia; the Department of Psychiatry, University of Bonn, Bonn, Germany; the Centre for Psychiatric Research, Aarhus University Hospital, Risskov, Denmark; the Biological Psychiatry Unit and Dual Diagnosis Ward, Istituto Di Ricovero e Cura a Carattere Scientifico, Centro San Giovanni di Dio, Fatebenefratelli, Brescia, Italy; the Central Institute of Mental Health, Division of Genetic Epidemiology in Psychiatry, Mannheim, Germany; the Laboratoire de Psychologie Médicale, Université Libre de Bruxelles and Psy Pluriel, Centre Européen de Psychologie Médicale, Brussels; the Institute of Public Health of the Republic of Slovenia, Ljubljana, Slovenia; the Department of Molecular and Biomedical Sciences, Jozef Stefan Institute, Ljubljana, Slovenia; the Clinic for Chronic Depression, Aarhus University Hospital, Risskov, Denmark; the Neurosciences Centre of Excellence in Drug Discovery, Glaxo­SmithKline R and D, Verona, Italy; the Department of Psychiatry, University of Toronto, Toronto; Computational Biology, GlaxoSmithKline Pharmaceuticals, Stevenage, Hertfordshire, United Kingdom; the Centre National de Genotypage, Evry Cedex, France. Address correspondence and reprint requests to Dr. Uher, P080 SGDP, Institute of Psychiatry, De Crespigny Park, SE5 8AF, London, United Kingdom; [email protected] (e-mail).