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Letters to the Editor
Published Online: 1 January 2024

Misinterpretations and Omissions: A Critical Response to Goodwin and Colleagues’ Commentary on Psilocybin-Assisted Therapy

Kelley C. O’Donnell, M.D., Ph.D. [email protected], Brian T. Anderson, M.D., Frederick S. Barrett, Ph.D., Michael P. Bogenschutz, M.D., Charles S. Grob, M.D., Peter S. Hendricks, Ph.D., Benjamin Kelmendi, M.D., Sandeep M. Nayak, M.D., Christopher R. Nicholas, Ph.D., Casey A. Paleos, M.D., Christopher S. Stauffer, M.D., and Natalie Gukasyan, M.D.Authors Info & Affiliations
Publication: American Journal of Psychiatry
Volume 181, Number 1
https://doi.org/10.1176/appi.ajp.20230661
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Information & Authors

Information

Published In

Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Volume 181 • Number 1 • January 01, 2024
Pages: 74 - 75

History

Received: 22 August 2023
Accepted: 8 November 2023
Published online: 1 January 2024
Published in print: January 01, 2024

Keywords

  1. Psychotherapy
  2. Pharmacotherapy
  3. Research Design and Methods

Authors

Affiliations

Kelley C. O’Donnell, M.D., Ph.D. [email protected]
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
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Brian T. Anderson, M.D.
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
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Frederick S. Barrett, Ph.D.
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
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Michael P. Bogenschutz, M.D.
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
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Charles S. Grob, M.D.
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
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Peter S. Hendricks, Ph.D.
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
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Benjamin Kelmendi, M.D.
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
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Sandeep M. Nayak, M.D.
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
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Christopher R. Nicholas, Ph.D.
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
View all articles by this author
Casey A. Paleos, M.D.
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
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Christopher S. Stauffer, M.D.
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
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Natalie Gukasyan, M.D.
Department of Psychiatry, NYU Grossman School of Medicine, New York, NYU Langone Center for Psychedelic Medicine, New York (O’Donnell, Bogenschutz); Department of Psychiatry & Behavioral Sciences, UCSF School of Medicine, San Francisco, UC Berkeley Center for the Science of Psychedelics, Berkeley, Calif. (Anderson); Department of Psychiatry and Behavioral Sciences, Center for Psychedelic and Consciousness Research, Department of Neuroscience, Department of Psychological and Brain Sciences, Johns Hopkins University School of Medicine, Baltimore (Barrett, Nayak); Johns Hopkins University, Baltimore (Barrett); Department of Psychiatry and Biobehavioral Sciences and Pediatrics, UCLA School of Medicine, Los Angeles (Grob); Department of Psychiatry and Behavioral Neurobiology, School of Medicine, University of Alabama at Birmingham, Birmingham, Ala. (Hendricks); Department of Psychiatry, Yale University School of Medicine, New Haven, Conn. (Kelmendi); Department of Family Medicine and Community Health, University of Wisconsin School of Medicine and Public Health, University of Wisconsin Transdisciplinary Center for Research in Psychoactive Substances, Madison, Wisc. (Nicholas); Nautilus Sanctuary, New York (Paleos); Social Neuroscience and Psychotherapy Lab, Department of Psychiatry, Oregon Health & Science University, Portland, Ore. (Stauffer); Department of Psychiatry, Columbia University Medical Center, New York State Psychiatric Institute, New York (Gukasyan).
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Notes

Send correspondence to Dr. O’Donnell ([email protected]).

Funding Information

Drs. O’Donnell, Paleos, Nicholas, and Stauffer receive payments from MAPS-Public Benefit Corporation (MPBC) as contractors to work on clinical trials and/or the education and supervision of research therapists. Dr. Gukasyan and Dr. Nayak have received research support from Usona Institute. Dr. Anderson has received consulting fees from Journey Colab. Dr. Barrett is a scientific advisor for WavePaths, Ltd, MindState Design Labs, LLC, and Gilgamesh Pharmaceuticals, Inc. He has received gift funding from the Wana Brand Foundation. Dr. Hendricks was previously in a paid advisory relationship with Silo Pharma and is currently in paid advisory relationships with the following organizations regarding the development of psychedelics and related compounds: Bright Minds Biosciences Ltd., Eleusis Benefit Corporation, Journey Colab Corporation, and Reset Pharmaceuticals Inc. Dr. Kelmendi serves as the Chief Scientific Advisor for Transcend Therapeutics and has served as a consultant for Ceruvia Lifesciences and Transcend Therapeutics. Dr. Bogenschutz reports research support from B.More, Inc., Dr. Bronner’s Family Foundation, the Fournier Family Foundation, the Heffter Research Institute, Bill Linton, Mind Medicine, Inc., the Multidisciplinary Association for Psychedelic Studies (MAPS) PBC, the Riverstyx Foundation, Tilray Canada, and the Turnbull Family Foundation. He has consulted for the Heffter Research Institute, and currently serves on the advisory boards of Ajna Labs LLC, Bright Minds Biosciences, Inc., and Journey Colab.

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