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Clinical Synthesis
Published Online: 1 July 2013

Clinical Considerations in the Evaluation and Management of Patients Following Traumatic Brain Injury

Abstract

TBI is recognized as the “signature wound” for military personnel in recent wars. The authors review the current literature on TBI diagnosis and treatment strategies and note areas where clinical controversies exist.

Abstract

Traumatic brain injury (TBI) is one of the most common causes of injury and disability, affecting about 1.7 million individuals annually in the U.S. Furthermore, TBI is also recognized as the “signature wound” for military personnel in recent wars. Both civilian and military TBIs result in individual, family, and societal economic and health costs. Even mild TBIs (i.e., concussions) can produce persistent difficulties in mental and physical well-being (e.g., problems with sleep, fatigue, pain, and cognitive functioning), which may be compounded by psychiatric comorbidities. Current treatment and management of the TBI patient typically involves case-by-case use of pharmacologic and/or cognitive-behavioral approaches that individually address post-TBI symptoms. We review the current literature on TBI diagnosis and treatment strategies and note areas where clinical controversies exist. It is hoped that through continued research (and discussion) of these important issues, a greater consensus on the science of treatment of TBI will be achieved.

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Published online: 1 July 2013
Published in print: Summer 2013

Authors

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Ashlee A. Heldreth, B.A., B.S.
Murray B. Stein, M.D., M.P.H.
Elizabeth W. Twamley, Ph.D.

Notes

Address correspondence to Henry J. Orff, Ph.D., VA San Diego Healthcare System, 9151B 3350 La Jolla Village Dr., San Diego, CA 92161; e-mail: [email protected]

Funding Information

Author Information and CME Disclosure
Henry J. Orff, Ph.D., Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System; and Department of Psychiatry, University of California, San Diego
Chelsea C. Hays, Research Service, VA San Diego Healthcare System
Ashlee A. Heldreth, B.A., B.S., School of Speech, Language, and Hearing Sciences, San Diego State University
Murray B. Stein, M.D., M.P.H., Department of Psychiatry, University of California, San Diego; Department of Family and Preventive Medicine, University of California, San Diego; and Psychiatry Service, VA San Diego Healthcare System
Elizabeth W. Twamley, Ph.D., Center of Excellence for Stress and Mental Health, VA San Diego Healthcare System; Psychiatry Service, VA San Diego Healthcare System; Department of Psychiatry, University of California, San Diego
All authors report no competing interests.
The authors acknowledge grant support from the VA Rehabilitation Research and Development Service (D7217-R to EWT) and the Department of Defense (W81XWH-08-2-0159, INTRuST Clinical Consortium, to MBS).

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