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Published Online: 1 January 2012

Symptom Profile and Etiology of Delirium in a Referral Population in Northern India: Factor Analysis of the DRS–R98

Publication: The Journal of Neuropsychiatry and Clinical Neurosciences

Abstract

Delirium is understudied in developing countries, where there tends to be a lower proportion of older persons and comorbid dementia. The authors assessed 100 consecutive cases of DSM-IV delirium (patients' mean age: 44.4 [standard deviation: 19.4] years; mean DRS–R98 score: 25.6 [3.6]) referred to an adult Consultation–Liaison Psychiatry service in Northern India. Disturbances of attention, orientation, visuospatial ability, and sleep disturbance were the most frequent symptoms, followed by language, thought-process abnormality, and motor agitation. A three-factor solution was identified, representing domains for cognition, higher-order thinking, and circadian rhythm/psychosis. These domains can guide studies addressing the relationship between symptom profile, therapeutic needs, and outcomes and are consistent with core domains previously identified in other countries.

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Information

Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Pages: 95 - 101
PubMed: 22450619

History

Received: 10 January 2011
Revision requested: 15 March 2011
Accepted: 20 April 2011
Published online: 1 January 2012
Published in print: Winter 2012

Keywords

  1. Delirium Rating Scale
  2. India

Authors

Details

Surendra K. Mattoo, M.D.
From the Dept. of Psychiatry, Postgraduate Institute of Medical Education & Research, Chandigarh, India (SKM, SG, KC); Lilly Research Laboratories, Indianapolis, IN, U.S. (PTT); University of Mississippi Medical School, U.S. (PTT); Tufts University School of Medicine, M.A., USA (PTT); Indiana University School of Medicine, IN, U.S. (PTT); Dept. of Adult Psychiatry, Midwestern Regional Hospital, and University of Limerick Medical School, Limerick, Ireland (DJM); South Staffs and Shropshire NHS Foundation Trust, Burton on Trent, D13 0RB, U.K. (NG).
Sandeep Grover, M.D.
From the Dept. of Psychiatry, Postgraduate Institute of Medical Education & Research, Chandigarh, India (SKM, SG, KC); Lilly Research Laboratories, Indianapolis, IN, U.S. (PTT); University of Mississippi Medical School, U.S. (PTT); Tufts University School of Medicine, M.A., USA (PTT); Indiana University School of Medicine, IN, U.S. (PTT); Dept. of Adult Psychiatry, Midwestern Regional Hospital, and University of Limerick Medical School, Limerick, Ireland (DJM); South Staffs and Shropshire NHS Foundation Trust, Burton on Trent, D13 0RB, U.K. (NG).
Kaustav Chakravarty, M.D.
From the Dept. of Psychiatry, Postgraduate Institute of Medical Education & Research, Chandigarh, India (SKM, SG, KC); Lilly Research Laboratories, Indianapolis, IN, U.S. (PTT); University of Mississippi Medical School, U.S. (PTT); Tufts University School of Medicine, M.A., USA (PTT); Indiana University School of Medicine, IN, U.S. (PTT); Dept. of Adult Psychiatry, Midwestern Regional Hospital, and University of Limerick Medical School, Limerick, Ireland (DJM); South Staffs and Shropshire NHS Foundation Trust, Burton on Trent, D13 0RB, U.K. (NG).
Paula T. Trzepacz, M.D.
From the Dept. of Psychiatry, Postgraduate Institute of Medical Education & Research, Chandigarh, India (SKM, SG, KC); Lilly Research Laboratories, Indianapolis, IN, U.S. (PTT); University of Mississippi Medical School, U.S. (PTT); Tufts University School of Medicine, M.A., USA (PTT); Indiana University School of Medicine, IN, U.S. (PTT); Dept. of Adult Psychiatry, Midwestern Regional Hospital, and University of Limerick Medical School, Limerick, Ireland (DJM); South Staffs and Shropshire NHS Foundation Trust, Burton on Trent, D13 0RB, U.K. (NG).
David J. Meagher, M.D.
From the Dept. of Psychiatry, Postgraduate Institute of Medical Education & Research, Chandigarh, India (SKM, SG, KC); Lilly Research Laboratories, Indianapolis, IN, U.S. (PTT); University of Mississippi Medical School, U.S. (PTT); Tufts University School of Medicine, M.A., USA (PTT); Indiana University School of Medicine, IN, U.S. (PTT); Dept. of Adult Psychiatry, Midwestern Regional Hospital, and University of Limerick Medical School, Limerick, Ireland (DJM); South Staffs and Shropshire NHS Foundation Trust, Burton on Trent, D13 0RB, U.K. (NG).
Nitin Gupta, M.D.
From the Dept. of Psychiatry, Postgraduate Institute of Medical Education & Research, Chandigarh, India (SKM, SG, KC); Lilly Research Laboratories, Indianapolis, IN, U.S. (PTT); University of Mississippi Medical School, U.S. (PTT); Tufts University School of Medicine, M.A., USA (PTT); Indiana University School of Medicine, IN, U.S. (PTT); Dept. of Adult Psychiatry, Midwestern Regional Hospital, and University of Limerick Medical School, Limerick, Ireland (DJM); South Staffs and Shropshire NHS Foundation Trust, Burton on Trent, D13 0RB, U.K. (NG).

Notes

Correspondence: Professor David Meagher, University of Limerick Medical School, Ireland; [email protected] (e-mail).

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