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Windows to the Brain
Published Online: 1 January 2013

Update on Mild Traumatic Brain Injury: Neuropathology and Structural Imaging

Publication: The Journal of Neuropsychiatry and Clinical Neurosciences

Abstract

In this installment of the Windows to the Brain series, the authors present detailed, graphic representation of neuronal injury for all levels of traumatic brain injury (TBI), including mild. We see representation of the swollen axon profiles characteristic of the “diffuse axonal injury” that produces transient focal deformations resulting from applied forces such as angular acceleration, pressure, and ballistic trauma, and, over time, the localized swelling that can become sufficient to rupture the axon. A challenge for the clinical follow-up of mild TBI is the presence of considerable differences across patients in the anatomic distribution of affected areas.

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Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Pages: 1 - 5
PubMed: 23487187

History

Published online: 1 January 2013
Published in print: Winter 2013

Authors

Details

Katherine H. Taber, Ph.D.
Drs. Taber and Hurley are affiliated with the Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center, and the W.G. Hefner Veterans Affairs Medical Center, in Salisbury, NC. Dr. Taber is affiliated with the Division of Biomedical Sciences at the Via College of Osteopathic Medicine, in Blacksburg, VA, and the Dept. of Physical Medicine and Rehabilitation at Baylor College of Medicine, in Houston, TX. Dr. Hurley is affiliated with the Depts. of Psychiatry and Radiology at Wake Forest School of Medicine, in Winston-Salem, NC, and the Menninger Dept. of Psychiatry and Behavioral Sciences at Baylor College of Medicine, in Houston, TX.
Robin A. Hurley, M.D.
Drs. Taber and Hurley are affiliated with the Veterans Affairs Mid-Atlantic Mental Illness Research, Education, and Clinical Center, and the W.G. Hefner Veterans Affairs Medical Center, in Salisbury, NC. Dr. Taber is affiliated with the Division of Biomedical Sciences at the Via College of Osteopathic Medicine, in Blacksburg, VA, and the Dept. of Physical Medicine and Rehabilitation at Baylor College of Medicine, in Houston, TX. Dr. Hurley is affiliated with the Depts. of Psychiatry and Radiology at Wake Forest School of Medicine, in Winston-Salem, NC, and the Menninger Dept. of Psychiatry and Behavioral Sciences at Baylor College of Medicine, in Houston, TX.

Notes

Address correspondence to Dr. Robin Hurley, Hefner VA Medical Center, Salisbury, NC; e-mail: [email protected]

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