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Published Online: 12 June 2015

Reliability and Validity of Proposed DSM-5 ADHD Symptoms in a Clinical Sample of Adults

Breno Matte, M.D., Luis Augusto Rohde, M.D., Ph.D., J. Blake Turner, Ph.D., Prudence W. Fisher, Ph.D., Sa Shen, Ph.D., Claiton H. D. Bau, M.D., Ph.D., Joel T. Nigg, Ph.D., and Eugenio H. Grevet, M.D., Ph.D.Authors Info & Affiliations
Publication: The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 27, Number 3
https://doi.org/10.1176/appi.neuropsych.13060137
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Abstract

The DSM-5 ADHD and Disruptive Behaviors Work Group proposed two major changes for diagnosis of attention deficit hyperactivity disorder (ADHD) in adults: 1) inclusion of four new impulsivity symptoms and 2) reduction in the number of symptoms required for assigning an ADHD diagnosis. In this case-control study, the performance of these modifications was assessed in a clinical sample of 133 adult subjects (68 ADHD cases and 65 non-ADHD control subjects). The proposed new impulsivity symptoms for adults do not improve ADHD diagnosis enough to overcome potential negative effects of changing the criteria. However, fewer symptoms than the six-of-nine threshold required by DSM-IV provided the best cutoff point for identifying adults who are impaired.

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Information & Authors

Information

Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 27 • Number 3 • Summer 2015
Pages: 228 - 236
PubMed: 26067434

History

Received: 21 June 2013
Accepted: 1 November 2013
Published online: 12 June 2015
Published in print: Summer 2015

Authors

Affiliations

Breno Matte, M.D.
From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN)
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Luis Augusto Rohde, M.D., Ph.D.
From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN)
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J. Blake Turner, Ph.D.
From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN)
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Prudence W. Fisher, Ph.D.
From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN)
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Sa Shen, Ph.D.
From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN)
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Claiton H. D. Bau, M.D., Ph.D.
From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN)
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Joel T. Nigg, Ph.D.
From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN)
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Eugenio H. Grevet, M.D., Ph.D.
From the ADHD Outpatient Program, Hospital de Clinicas de Porto Alegre (BM, LAR, CHDB, EHG), and Dept. of Genetics, Instituto de Biociências (CHDB), Federal University of Rio Grande do Sul, Porto Alegre, Brazil; National Institute of Developmental Psychiatry for Children and Adolescents, São Paulo, Brazil (LAR); Columbia University/New York State Psychiatric Institute, New York, NY (JBT, PWF, SS); and Dept. of Psychiatry, Oregon Health and Sciences University, Portland, OR (JTN)
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Notes

Send correspondence to Breno Matte, M.D.; e-mail: [email protected]

Funding Information

Dr. Rohde was on the speakers’ bureau/advisory board and/or acted as a consultant for Eli Lilly, Janssen-Cilag, Novartis, and Shire in the last 3 years. He also received travel awards (airline tickets and hotel) from Janssen-Cilag and Novartis in 2010 to take part in two child psychiatric meetings. The ADHD and Juvenile Bipolar Disorder Outpatient Programs chaired by Dr. Rohde received unrestricted educational and research support from the following pharmaceutical companies in the last 3 years: Abbott, Eli Lilly, Janssen-Cilag, Novartis, and Shire. All other authors report no financial relationships with commercial interests.

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