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Special Article
Published Online: 4 December 2024

Functional Vision Loss Among Adults and Children: Literature Review and Comparative Analysis

Publication: The Journal of Neuropsychiatry and Clinical Neurosciences

Abstract

Objective:

The purpose of this study was to compare functional vision loss (FVL) among adults and children, including its presentation and the biopsychosocial factors that may contribute to FVL development.

Methods:

PubMed, Scopus, and PsycInfo databases were searched in April 2023 for studies reporting data on visual acuity loss (VAL), visual field defects (VFDs), psychiatric disorders, or biopsychosocial stressors of patients with FVL. Studies were excluded if they did not report information on the specific outcomes for all patients or reported on only a subset of FVL patients.

Results:

Overall, 27 studies were included, comprising 1,476 patients. Twenty-six articles reported on visual symptoms, 14 on psychiatric disorders, and 11 on biopsychosocial stressors. The prevalence of VAL was similar among adults (80%) compared with children (83%), but VFDs were significantly more common among adults (86% in adults vs. 50% in children). The prevalence of a history of psychiatric disorders was similar among both adults (42%) and children (23%). Adults most commonly reported accidents or physical trauma (31%) as predisposing or precipitating factors for VAL, whereas children most frequently reported family or home stress (19%).

Conclusions:

VFDs were found to be more common among adults than among children with FVL. Among adults and children with FVL, different psychiatric and biopsychosocial stressors were reported. This review was limited by the heterogeneous data among studies and unstandardized methods of data collection and reporting. Future research may seek to better understand the differences between adults and children with FVL and explore possible treatment options.

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Information & Authors

Information

Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
PubMed: 39628281

History

Received: 2 February 2024
Revision received: 18 June 2024
Accepted: 22 August 2024
Published online: 4 December 2024

Keywords

  1. Functional Vison Loss
  2. Neuro-ophthalmology
  3. Somatoform Disorder
  4. Visual Field Defects
  5. Non-Organic Vision Loss

Authors

Details

Parker D. Brady, M.D., M.P.H.
Department of Ophthalmology (Brady) and Department of Neurology, Section on Statistical Planning and Analysis (Hernandez, Salter), University of Texas Southwestern Medical Center, Dallas; independent researcher, Dallas (Truong-Le).
Roberto Sergio Hernandez, Ph.D.
Department of Ophthalmology (Brady) and Department of Neurology, Section on Statistical Planning and Analysis (Hernandez, Salter), University of Texas Southwestern Medical Center, Dallas; independent researcher, Dallas (Truong-Le).
Amber Salter, Ph.D.
Department of Ophthalmology (Brady) and Department of Neurology, Section on Statistical Planning and Analysis (Hernandez, Salter), University of Texas Southwestern Medical Center, Dallas; independent researcher, Dallas (Truong-Le).
Melanie Truong-Le, D.O., O.D. [email protected]
Department of Ophthalmology (Brady) and Department of Neurology, Section on Statistical Planning and Analysis (Hernandez, Salter), University of Texas Southwestern Medical Center, Dallas; independent researcher, Dallas (Truong-Le).

Notes

Send correspondence to Dr. Truong-Le ([email protected]).
Presented at the annual meeting of the North American Neuro-Ophthalmology Society, Orlando, Fla., March 11–16, 2023.

Competing Interests

Dr. Salter reports receiving research funding from the Consortium of Multiple Sclerosis Centers and the Department of Defense Congressionally Directed Medical Research Program, the Multiple Sclerosis Society of Canada, and the National Multiple Sclerosis Society; being an editorial board member for Neurology; serving as a consultant for Abata Therapeutics, Gryphon Bio, and Sora Neuroscience; being a member of the data and safety monitoring boards for Central Vein Sign; and being a shareholder with Owl Therapeutics. The other authors report no financial relationships with commercial interests.

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