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Published Online: 1 January 2011

Evidence-Based Treatments of Addiction

Abstract

Both pharmacotherapy and behavioural treatment are required to relieve the symptoms of addictive disorders. This paper reviews the evidence for the benefits of pharmacotherapy and discusses mechanisms where possible. Animal models of addiction have led to some medications that are effective in reducing symptoms and improving function but they do not produce a cure. Addiction is a chronic disease that tends to recur when treatment is stopped; thus, long-term treatment is recommended.
(Reprinted with permission from Philosophical Transactions of the Royal Society B: Biological Sciences 2008; 363:3277–3286)

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Published online: 1 January 2011
Published in print: Winter 2011

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