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Published Online: 1 November 2001

Subtle Prefrontal Neuropathology in a Pilot Magnetic Resonance Spectroscopy Study in Patients With Borderline Personality Disorder

Ludger Tebartz van Elst, M.D., Thorsten Thiel, Ph.D., Bernd Hesslinger, M.D., Klaas Lieb, M.D., Martin Bohus, M.D., Jürgen Hennig, Ph.D., and Dieter Ebert, M.D.Authors Info & Affiliations
Publication: The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 13, Number 4
https://doi.org/10.1176/jnp.13.4.511
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Abstract

The authors examined the brains of patients with borderline personality disorder (BPD) by using short echo time single voxel spectroscopy and found a significant 19% reduction of absolute N-acetylaspartate concentrations in the dorsolateral prefrontal cortex in BPD (P=0.01) compared with control subjects.

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Information

Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 13 • Number 4 • November 2001
Pages: 511 - 514
PubMed: 11748321

History

Published online: 1 November 2001
Published in print: November 2001

Authors

Details

Ludger Tebartz van Elst, M.D.
Received April 13, 2001; revised June 20, 2001; accepted June 27, 2001. From the Department of Psychiatry and Psychotherapy and Department of Radiology, Albert-Ludwigs-University, Freiburg, Germany. Address correspondence to Dr. Tebartz van Elst, Department of Psychiatry and Psychotherapy, Hauptstr. 5; 79104 Freiburg - Germany. E-mail: [email protected].
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Thorsten Thiel, Ph.D.
Received April 13, 2001; revised June 20, 2001; accepted June 27, 2001. From the Department of Psychiatry and Psychotherapy and Department of Radiology, Albert-Ludwigs-University, Freiburg, Germany. Address correspondence to Dr. Tebartz van Elst, Department of Psychiatry and Psychotherapy, Hauptstr. 5; 79104 Freiburg - Germany. E-mail: [email protected].
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Bernd Hesslinger, M.D.
Received April 13, 2001; revised June 20, 2001; accepted June 27, 2001. From the Department of Psychiatry and Psychotherapy and Department of Radiology, Albert-Ludwigs-University, Freiburg, Germany. Address correspondence to Dr. Tebartz van Elst, Department of Psychiatry and Psychotherapy, Hauptstr. 5; 79104 Freiburg - Germany. E-mail: [email protected].
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Klaas Lieb, M.D.
Received April 13, 2001; revised June 20, 2001; accepted June 27, 2001. From the Department of Psychiatry and Psychotherapy and Department of Radiology, Albert-Ludwigs-University, Freiburg, Germany. Address correspondence to Dr. Tebartz van Elst, Department of Psychiatry and Psychotherapy, Hauptstr. 5; 79104 Freiburg - Germany. E-mail: [email protected].
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Martin Bohus, M.D.
Received April 13, 2001; revised June 20, 2001; accepted June 27, 2001. From the Department of Psychiatry and Psychotherapy and Department of Radiology, Albert-Ludwigs-University, Freiburg, Germany. Address correspondence to Dr. Tebartz van Elst, Department of Psychiatry and Psychotherapy, Hauptstr. 5; 79104 Freiburg - Germany. E-mail: [email protected].
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Jürgen Hennig, Ph.D.
Received April 13, 2001; revised June 20, 2001; accepted June 27, 2001. From the Department of Psychiatry and Psychotherapy and Department of Radiology, Albert-Ludwigs-University, Freiburg, Germany. Address correspondence to Dr. Tebartz van Elst, Department of Psychiatry and Psychotherapy, Hauptstr. 5; 79104 Freiburg - Germany. E-mail: [email protected].
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Dieter Ebert, M.D.
Received April 13, 2001; revised June 20, 2001; accepted June 27, 2001. From the Department of Psychiatry and Psychotherapy and Department of Radiology, Albert-Ludwigs-University, Freiburg, Germany. Address correspondence to Dr. Tebartz van Elst, Department of Psychiatry and Psychotherapy, Hauptstr. 5; 79104 Freiburg - Germany. E-mail: [email protected].
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