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Published Online: 1 February 2006

Serotonin Transporter Gene Promoter Region Polymorphism Associated With Poststroke Major Depression

Rajamannar Ramasubbu, M.D., MRCPsych, F.R.C.Psych.(C), M.Sc., Rose Tobias, BSc, R.T., Alastair M. Buchan, M.D., and N. Torben Bech-Hansen, Ph.D.Authors Info & Affiliations
Publication: The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 18, Number 1
https://doi.org/10.1176/jnp.18.1.96
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Abstract

The authors examined variations of serotonin transporter-linked promoter region (5-HTTLPR) functional polymorphism in 26 stroke patients with major depression and in 25 unrelated nondepressed stroke subjects of Caucasian descent. Findings indicate a significant association between 5-HTTLPR short variant genotype and poststroke major depression.

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Published In

Go to The Journal of Neuropsychiatry and Clinical Neurosciences
Go to The Journal of Neuropsychiatry and Clinical Neurosciences
The Journal of Neuropsychiatry and Clinical Neurosciences
Volume 18 • Number 1 • February 2006
Pages: 96 - 99
PubMed: 16525076

History

Published online: 1 February 2006
Published in print: February 2006

Authors

Details

Rajamannar Ramasubbu, M.D., MRCPsych, F.R.C.Psych.(C), M.Sc.
Received September 24, 2004; revised August 3, 2005; accepted August 9, 2005. From the Departments of Psychiatry, Clinical Neurosciences, and Medical Genetics, University of Calgary., Alberta, Canada. Address correspondence to Dr. Ramasubbu, Department of Psychiatry and Clinical Neurosciences, University of Calgary, Special Services Building, Rm. AW258A, 1403, 29th Street N.W., Calgary, Alberta, Canada, T2N 2T9; [email protected] (E-mail).
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Rose Tobias, BSc, R.T.
Received September 24, 2004; revised August 3, 2005; accepted August 9, 2005. From the Departments of Psychiatry, Clinical Neurosciences, and Medical Genetics, University of Calgary., Alberta, Canada. Address correspondence to Dr. Ramasubbu, Department of Psychiatry and Clinical Neurosciences, University of Calgary, Special Services Building, Rm. AW258A, 1403, 29th Street N.W., Calgary, Alberta, Canada, T2N 2T9; [email protected] (E-mail).
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Alastair M. Buchan, M.D.
Received September 24, 2004; revised August 3, 2005; accepted August 9, 2005. From the Departments of Psychiatry, Clinical Neurosciences, and Medical Genetics, University of Calgary., Alberta, Canada. Address correspondence to Dr. Ramasubbu, Department of Psychiatry and Clinical Neurosciences, University of Calgary, Special Services Building, Rm. AW258A, 1403, 29th Street N.W., Calgary, Alberta, Canada, T2N 2T9; [email protected] (E-mail).
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N. Torben Bech-Hansen, Ph.D.
Received September 24, 2004; revised August 3, 2005; accepted August 9, 2005. From the Departments of Psychiatry, Clinical Neurosciences, and Medical Genetics, University of Calgary., Alberta, Canada. Address correspondence to Dr. Ramasubbu, Department of Psychiatry and Clinical Neurosciences, University of Calgary, Special Services Building, Rm. AW258A, 1403, 29th Street N.W., Calgary, Alberta, Canada, T2N 2T9; [email protected] (E-mail).
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