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Published Online: 1 April 2011

The Influence of Thyroid Function on Cognition in a Sample of Ethnically Diverse, Rural-Dwelling Women: A Project FRONTIER Study

Leigh A. Johnson, Ph.D., Valerie Hobson, M.A., Marjorie Jenkins, M.D., Andrew Dentino, M.D., R. Michael Ragain, M.D., M.S. Ed., and Sid O'Bryant, Ph.D.Authors Info & Affiliations

Publication: The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 23, Number 2

https://doi.org/10.1176/jnp.23.2.jnp219

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Abstract

This study examined the influence of thyroid markers (TSH and FT4) on cognition in a sample of rural-dwelling women. Data were analyzed from 81 women who were enrolled in an ongoing study of rural health, Project FRONTIER. Cognition was assessed with the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). TSH levels were significantly related to the RBANS Attention Index, and FT4 levels were significantly related to the RBANS Language Index. The current study found that TSH and FT4 were differentially related to neurocognitive domains, with TSH being related only to measures of attention and FT4 to measures of language.

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Information & Authors

Information

Published In

The Journal of Neuropsychiatry and Clinical Neurosciences

Volume 23 • Number 2 • Spring 2011

Pages: 219 - 222

PubMed: 21677255

History

Received: 23 October 2009

Revision received: 15 January 2010

Accepted: 9 February 2010

Published online: 1 April 2011

Published in print: Spring 2011

Authors

Affiliations

Leigh A. Johnson, Ph.D.

From the Laura W. Bush Institute for Women's Health, Texas Tech University Health Sciences Center, Amarillo; Department of Family and Community Medicine, Texas Tech University Health Sciences Center, Lubbock; Department of Psychology, Texas Tech University, Lubbock; Department of Obstetrics and Gynecology, Texas Tech University Health Sciences Center, Amarillo; Division of Geriatric and Palliative Medicine, Departments of Internal Medicine and Psychiatry, Texas Tech University Health Sciences Center, Lubbock; Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock; F. Marie Hall Institute for Rural & Community Health, Texas Tech Health Sciences Center, Lubbock; Department of Neurology, Texas Tech University Health Sciences Center, Lubbock.

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Valerie Hobson, M.A.

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Marjorie Jenkins, M.D.

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Andrew Dentino, M.D.

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R. Michael Ragain, M.D., M.S. Ed.

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Sid O'Bryant, Ph.D.

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Notes

Send correspondence to Sid O'Bryant, Ph.D., Department of Family and Community Medicine, Texas Tech University Health Sciences Center, 3601 4^th St., Lubbock, TX 79430; [email protected] (e-mail).

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The Influence of Thyroid Function on Cognition in a Sample of Ethnically Diverse, Rural-Dwelling Women: A Project FRONTIER Study

Abstract

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