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Published Online: March 1952

LIPOPROTEINS IN GENERAL AND CEREBRAL ARTERIOSCLEROSIS : Preliminary Report

Publication: American Journal of Psychiatry

Abstract

1. Lipoprotein levels (St 10-20 class) of a group of patients diagnosed as psychosis with cerebral arteriosclerosis display little significant difference from a group of normals of similar age. If the level of lipoproteins (St 10-20 class) is a reflection of the activity of atheroma formation, then these patients show no more atherosclerotic activity than presumably normal individuals of the same age.
2. The autopsy findings in 24 cases suggest that cerebral atherosclerosis plays an insignificant role in so-called psychosis with cerebral arteriosclerosis, the latter being due either to senile or arteriolosclerotic changes. There appears to be a trend to more "lipoidosis" as observed in the aorta, coronary, and cerebral vessels, with increasing levels of St 10-20 lipoproteins in the blood serum.

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Published In

Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 663 - 668
PubMed: 14903194

History

Published in print: March 1952
Published online: 1 April 2006

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ALEXANDER SIMON
The Division of Psychiatry, University of California School of Medicine, San Francisco, the Division of Medical Physics, University of California, Berkeley, and The Langley Porter Clinic, Department of Mental Hygiene, State of California, San Francisco.
JOHN W. GOFMAN
The Division of Psychiatry, University of California School of Medicine, San Francisco, the Division of Medical Physics, University of California, Berkeley, and The Langley Porter Clinic, Department of Mental Hygiene, State of California, San Francisco.
NATHAN MALAMUD
The Division of Psychiatry, University of California School of Medicine, San Francisco, the Division of Medical Physics, University of California, Berkeley, and The Langley Porter Clinic, Department of Mental Hygiene, State of California, San Francisco.
HARDIN B. JONES
The Division of Psychiatry, University of California School of Medicine, San Francisco, the Division of Medical Physics, University of California, Berkeley, and The Langley Porter Clinic, Department of Mental Hygiene, State of California, San Francisco.
FRANK T. LINDGREN
The Division of Psychiatry, University of California School of Medicine, San Francisco, the Division of Medical Physics, University of California, Berkeley, and The Langley Porter Clinic, Department of Mental Hygiene, State of California, San Francisco.

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