BROMIDE INTOXICATION AND QUANTITATIVE DETERMINATION IN SERUM

Five cases were presented illustrating several principles for the prescribing of bromide medication. A case is reported of an unprecedented serum bromide value as determined by the modified Wuth method. The suggestions that very high bromide findings are erroneous warrant further controlled studies. A few reports of similar findings are not conclusive for condemnation of a method in use for 30 years. Physicians and druggists still need warning against indiscriminate dispensing of bromides. Bromides may be mild but not harmless—they are usually taken by persons incapable of exercising good judgment or moderation. Dispensing without a physician's prescription should be prohibited.