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Published Online: December 1965

DESIPRAMINE AND IMIPRAMINE IN AN OUTPATIENT SETTING: A COMPARATIVE STUDY

H. G. LAFAVE, B. W. MARCH, A. K. KARGAS, and S. Y. SHUFFLERAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 122, Number 6

https://doi.org/10.1176/ajp.122.6.698

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Abstract

In a comparative study, 40 outpatients, each having a depressive syndrome as the principal clinical feature, were treated with either desipramine or imipramine. Fourteen patients on each drug completed the study. The efficacy of both drugs as antidepressants was found to be in the same range. Desipramine had a more rapid onset of action than imipramine and produced slightly fewer side effects. The difference between the number of days for onset of action and the number of side effects with both drugs is not statistically significant. The majority of patients on each drug responded well to treatment.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 122 • Number 6 • December 1965

Pages: 698 - 701

PubMed: 5845559

History

Published in print: December 1965

Published online: 1 April 2006

Authors

Details

H. G. LAFAVE

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B. W. MARCH

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A. K. KARGAS

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S. Y. SHUFFLER

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Superintendent, Saskatchewan Hospital, Weyburn, Saskatchewan, Canada

Deputy Superintendent, Saskatchewan Hospital, Weyburn, Saskatchewan, Canada

Senior Psychiatrist Saskatchewan Hospital, Weyburn, Saskatchewan, Canada

Research Assistant, Saskatchewan Hospital, Weyburn, Saskatchewan, Canada

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DESIPRAMINE AND IMIPRAMINE IN AN OUTPATIENT SETTING: A COMPARATIVE STUDY

Abstract

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