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Research Article
Published Online: April 1993

Association of nonsuppression of cortisol on the DST with primary polydipsia in chronic schizophrenia

Publication: American Journal of Psychiatry

Abstract

Thirteen polydipsic and 40 nonpolydipsic chronic schizophrenic patients received the dexamethasone suppression test while stabilized on psychotropic medication regimens. Thirty-eight percent (N = 5) of those with polydipsia but only 5% (N = 2) of those without polydipsia were nonsuppressors of cortisol (i.e., had an abnormal response). It is suggested that hippocampal dysfunction could cause both polydipsia and cortisol dysregulation in these patients.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 653 - 655
PubMed: 8465887

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Published in print: April 1993
Published online: 1 April 2006

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