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Published Online: April 1979

Urinary Excretion of Dimethyltryptamine in Liver Disease

Stuart A. Checkley, B.A., B.M., B.CH., Michael C.H. Oon, B.SC., PH.D., Richard Rodnight, B.SC., PH.D., D.SC., Marian P. Murphy, Roger S. Williams, M.D., and James L.T. Birley, M.B., CH.B., D.P.H.Authors Info & Affiliations
Publication: American Journal of Psychiatry
Volume 136, Number 4A
https://doi.org/10.1176/ajp.1979.136.4a.439
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Abstract

The urinary excretion of N, N-dimethyltryptamine (DMT) was higher in patients with severe liver disease than in normal subjects. This difference remained significant when patients with all grades of hepatic encephalopathy were excluded. Patients with liver disease whose mental states were normal excreted amounts of DMT similar to those of patients with a hospital diagnosis of schizophrenia.

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Information & Authors

Information

Published In

Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Volume 136 • Number 4A • April 1979
Pages: 439 - 441
PubMed: 284722

History

Received: 12 December 1977
Revision received: 13 February 1978
Accepted: 16 March 1978
Published in print: April 1979
Published online: 24 April 2020

Authors

Details

Stuart A. Checkley, B.A., B.M., B.CH.
Dr. Birley is the Dean of the Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, where Dr. Rodnight is Professor of Neurochemistry and Drs. Checkley and Don are research workers in the Departments of Psychiatry and Biochemistry. Dr. Williams is the Director of the Liver Research Unit, King’s College Hospital, London. Address reprint requests to Dr. Rodnight.
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Michael C.H. Oon, B.SC., PH.D.
Dr. Birley is the Dean of the Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, where Dr. Rodnight is Professor of Neurochemistry and Drs. Checkley and Don are research workers in the Departments of Psychiatry and Biochemistry. Dr. Williams is the Director of the Liver Research Unit, King’s College Hospital, London. Address reprint requests to Dr. Rodnight.
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Richard Rodnight, B.SC., PH.D., D.SC.
Dr. Birley is the Dean of the Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, where Dr. Rodnight is Professor of Neurochemistry and Drs. Checkley and Don are research workers in the Departments of Psychiatry and Biochemistry. Dr. Williams is the Director of the Liver Research Unit, King’s College Hospital, London. Address reprint requests to Dr. Rodnight.
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Marian P. Murphy
Dr. Birley is the Dean of the Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, where Dr. Rodnight is Professor of Neurochemistry and Drs. Checkley and Don are research workers in the Departments of Psychiatry and Biochemistry. Dr. Williams is the Director of the Liver Research Unit, King’s College Hospital, London. Address reprint requests to Dr. Rodnight.
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Roger S. Williams, M.D.
Dr. Birley is the Dean of the Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, where Dr. Rodnight is Professor of Neurochemistry and Drs. Checkley and Don are research workers in the Departments of Psychiatry and Biochemistry. Dr. Williams is the Director of the Liver Research Unit, King’s College Hospital, London. Address reprint requests to Dr. Rodnight.
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James L.T. Birley, M.B., CH.B., D.P.H.
Dr. Birley is the Dean of the Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, where Dr. Rodnight is Professor of Neurochemistry and Drs. Checkley and Don are research workers in the Departments of Psychiatry and Biochemistry. Dr. Williams is the Director of the Liver Research Unit, King’s College Hospital, London. Address reprint requests to Dr. Rodnight.
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