EFFECTS OF VITAMIN B₁ IN SCHIZOPHRENIA

L. H. ChaseAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 95, Number 5

https://doi.org/10.1176/ajp.95.5.1035

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Abstract

1. Ten schizophrenic male patients were given large doses of synthetic vitamin B₁ orally and intravenously for a period of eight weeks.

2. None showed clinical improvement that could be correlated with the medication. No deleterious effects were seen.

3. The Stanford-Binet scores showed only random changes.

4. No significant changes were observed in blood pressure, pulse rate, oxygen consumption rate, venous carbon dioxide and glutathione levels.

5. Decreases in venous oxygen and lactic acid levels were observed.

6. Three patients were given in addition four weekly injections of vitamin B₁ intrathecally without significant effects.

7. Extension of the study with other catalytic agents is regarded as desirable.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 95 • Number 5 • March 1939

Pages: 1035 - 1038

History

Published in print: March 1939

Published online: 1 April 2006

Authors

Details

L. H. Chase

The Research Service, Worcester State Hospital, Worcester, Mass.

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EFFECTS OF VITAMIN B₁ IN SCHIZOPHRENIA

Abstract

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