CEREBRAL DAMAGE IN HYPOGLYCEMIA : A Review.

A. B. BAKERAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 96, Number 1

https://doi.org/10.1176/ajp.96.1.109

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Abstract

1. The literature on those studies describing cerebral damage in hypoglycemia is reviewed.

2. Four sources of material underly this study—namely, insulin shock in diabetics, spontaneous hypoglycemia secondary to neoplasm or functional overactivity of the islands of Langerhans, insulin shock therapy in mental disorders, and experimental hypoglycemia in animals.

3. Four personal cases are reported, three of whom are still alive but handicapped by varying neurological and psychiatric disabilities.

4. From a review of the literature and a study of our own cases it seems very apparent that continued repeated hypoglycemia may definitely produce a depression of the cerebral function and even an irreversible degeneration of the brain tissue and cells, resulting in long continued or permanent functional damage or even death.

5. The factors behind the different individual responses to hypoglycemic insults are at present unknown, hence making it impossible to predict or adequately control the more severe reactions or the resulting brain damage.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 96 • Number 1 • July 1939

Pages: 109 - 127

History

Published in print: July 1939

Published online: 1 April 2006

Authors

Affiliations

A. B. BAKER

The division of nervous and mental diseases, University of Minnesota Medical School, Minneapolis.

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CEREBRAL DAMAGE IN HYPOGLYCEMIA : A Review.

Abstract

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