No access

Article

Published Online: November 1945

AGEING AND DETOXICATION : Studies in Hippuric Acid Synthesis During Psychoses of the Involutional and Old Age Group

KARL STERN, EWART G. HINDS, and BRIGITTE A. ASKONASAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 102, Number 3

https://doi.org/10.1176/ajp.102.3.325

Get Access

Abstract

The detoxifying capacity of the organism during psychoses of the involutional and old age period was investigated by Quick's intravenous hippuric acid test. Seventy-one patients were studied, 48 of whom were 45 years and older; 30 of these were 6o years and older.

Evidence of faulty detoxication was present in more than three times the number of patients of 6o years and older, than had been found by previous investigators in mentally normal people of the same age group. Moreover, a small group (5) of cases of senile dementia had conspicuously low values, even when compared with patients of the same age suffering from affective disorders or from hypertensive encephalopathy.

A comparison of these cases among themselves shows that gross differences in diet and nutrition, differences in body weight, in blood pressure and in urinary excretion can be neglected as sources of error.

The significance of these findings is discussed.

Get full access to this article

View all available purchase options and get full access to this article.

Get Access

Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 102 • Number 3 • November 1945

Pages: 325 - 329

PubMed: 21007679

History

Published in print: November 1945

Published online: 1 April 2006

Authors

Affiliations

KARL STERN

The Department of Psychiatry, McGill University, the Allan Memorial Institute of Psychiatry, and the Verdun Protestant Hospital.

View all articles by this author

EWART G. HINDS

The Department of Psychiatry, McGill University, the Allan Memorial Institute of Psychiatry, and the Verdun Protestant Hospital.

View all articles by this author

BRIGITTE A. ASKONAS

The Department of Psychiatry, McGill University, the Allan Memorial Institute of Psychiatry, and the Verdun Protestant Hospital.

View all articles by this author

Metrics & Citations

Metrics

Citations

Export Citations

If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download.

For more information or tips please see 'Downloading to a citation manager' in the Help menu.

Format	RIS (ProCite, Reference Manager) EndNote BibTex Medlars RefWorks
Direct importt
Citation style
Style

Copy to clipboard
Tips for downloading citations

There are no citations for this item

View Options

Get Access

Login options

Already a subscriber? Access your subscription through your login credentials or your institution for full access to this article.

Personal login Institutional Login Open Athens login

Purchase Options

Purchase this article to access the full text.

PPV Articles - American Journal of Psychiatry

Not a subscriber?

Subscribe Now / Learn More

PsychiatryOnline subscription options offer access to the DSM-5-TR^® library, books, journals, CME, and patient resources. This all-in-one virtual library provides psychiatrists and mental health professionals with key resources for diagnosis, treatment, research, and professional development.

Need more help? PsychiatryOnline Customer Service may be reached by emailing [email protected] or by calling 800-368-5777 (in the U.S.) or 703-907-7322 (outside the U.S.).

AGEING AND DETOXICATION : Studies in Hippuric Acid Synthesis During Psychoses of the Involutional and Old Age Group

Abstract

Get full access to this article