CEREBRAL ATROPHY IN PSYCHIATRIC PATIENTS

DEWEY K. ZIEGLERAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 111, Number 6

https://doi.org/10.1176/ajp.111.6.454

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Abstract

1. The early clinical symptoms of 40 patients with cerebral atrophy subsequently demonstrated by pneumoencephalogram are reviewed. In 25 cases the earliest abnormalities noted were not memory loss or impairment, but paranoid ideas, depression, neurosis, or psychopathy.

2. Clinical data of the patients with cerebral atrophy were compared with those of a control group who were suspected of having cerebral atrophy, but had normal pneumoencephalograms. The diagnosis of cerebral atrophy is found to be positively correlated with 3 factors: (a) presence of memory impairment by history or examination, (b) presence of abnormal findings on neurological examination, and (c) age over 40.

With the absence of any 1of these factors the probability of demonstrating cerebral atrophy radiologically is considerably diminished and with the absence of any 2 the probability becomes extremely small.

3. Cerebral atrophy was found in 5 patients with depression, of the 40-60 age group, without evidence of memory impairment or abnormalities in the neurological examination.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 111 • Number 6 • December 1954

Pages: 454 - 458

PubMed: 13207430

History

Published in print: December 1954

Published online: 1 April 2006

Authors

Affiliations

DEWEY K. ZIEGLER

The Boston Psychopathic Hospital and Department of Psychiatry, Harvard Medical School.

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CEREBRAL ATROPHY IN PSYCHIATRIC PATIENTS

Abstract

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