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Published Online: November 1955

ADRENOCORTICAL FUNCTION IN SCHIZOPHRENIA

EUGENE L. BLISS, CLAUDE J. MIGEON, C. H. HARDIN BRANCH, and LEO T. SAMUELSAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 112, Number 5

https://doi.org/10.1176/ajp.112.5.358

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Abstract

Adrenocortical function of chronic schizophrenics was investigated. The concentration of adrenal steroids (17-hydroxycorticosteroids) in the peripheral blood was determined at 8 am.; after the intravenous administration of various amounts of ACTH or of a pryogenic substance (Piromen); and after the subcutaneous injection of regular insulin. These drugs were employed to assess adrenocortical and pituitary-adrenocortical responsivity. Similar studies were made upon a comparable group of normal subjects. The adrenocortical and pituitary-adrenocortical reactivity of chronic schizophrenic and normal subjects were equivalent. There was no evidence of any impairment of adrenocortical physiology in the chronic schizophrenic patient.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 112 • Number 5 • November 1955

Pages: 358 - 365

PubMed: 13268715

History

Published in print: November 1955

Published online: 1 April 2006

Authors

Details

EUGENE L. BLISS

The Departments of Psychiatry and Biological Chemistry, University of Utah College of Medicine, Salt Lake City, Utah.

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CLAUDE J. MIGEON

The Departments of Psychiatry and Biological Chemistry, University of Utah College of Medicine, Salt Lake City, Utah.

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C. H. HARDIN BRANCH

The Departments of Psychiatry and Biological Chemistry, University of Utah College of Medicine, Salt Lake City, Utah.

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LEO T. SAMUELS

The Departments of Psychiatry and Biological Chemistry, University of Utah College of Medicine, Salt Lake City, Utah.

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ADRENOCORTICAL FUNCTION IN SCHIZOPHRENIA

Abstract

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