A CLINICAL TRIAL OF ALPHA-METHYLDOPA IN ELATED STATES

LOREN R. MOSHER, GERALD L. KLERMAN, and JOSEPH F. GREANEYAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 122, Number 10

https://doi.org/10.1176/ajp.122.10.1185

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Abstract

A clinical trial of alpha-methyldopa (Aldomet) in elated states is reported. Four drug trials were conducted in three "manic" patients at dosage levels up to 6 gms. per day. No therapeutic effect was noted, although a pharmacologic effect as evidenced by a fall in blood pressure in three of four trials was noted. However, further studies with this compound in psychiatric patients are indicated before final conclusions can be drawn.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 122 • Number 10 • April 1966

Pages: 1185 - 1188

PubMed: 5325470

History

Published in print: April 1966

Published online: 1 April 2006

Authors

Details

LOREN R. MOSHER

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GERALD L. KLERMAN

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JOSEPH F. GREANEY

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Clinical Associate, Section on Twin and Sibling Studies, National Institute of Mental Health, Bethesda, Md.

Associate Professor of Psychiatry, Yale University Medical School, New Haven, Conn.

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A CLINICAL TRIAL OF ALPHA-METHYLDOPA IN ELATED STATES

Abstract

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