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Published Online: September 1970

Placebo-Control Evaluation of Desipramine in Depression

Publication: American Journal of Psychiatry

Abstract

A double-blind clinical trial was conducted to compare the effectiveness of desipramine and placebo in newly hospitalized patients. Analysis of data from 74 patients (34 on desipramine, 40 on placebo) showed that in patients with endogenous depression, the response to desipramine was superior to response to placebo as early as the fifth day of treatment; in patients with neurotic (reactive) depression, no significant differences in response were found.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 335 - 338
PubMed: 4917855

History

Published in print: September 1970
Published online: 1 April 2006

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Assistant superintendent, Camarillo State Hospital, Camarillo, Calif. 93010
Senior psychiatrist in the adolescent treatment center, Camarillo State Hospital, Camarillo, Calif. 93010

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