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Published Online: January 1972

Perceptual Challenge to Measure Illness and Therapy

AMEDEO S. MARRAZZI, SHARON WOODRUFF, and DENIS KENNEDYAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 128, Number 7

https://doi.org/10.1176/ajp.128.7.886

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Abstract

The dissociation produced in the auditory modality by a challenge with LSD can be quantitated by an instrumental perception test. Chlorpromazine can protect against this dissociation, and its efficacy can be measured by changes in auditory perception. The author describes this quantitative instrumental procedure. which is being developed into a "clinical yardstick" to measure dissociative mental dysfunction and illness, its intensity, and its response to therapy.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 128 • Number 7 • January 1972

Pages: 886 - 890

PubMed: 5009270

History

Published in print: January 1972

Published online: 1 April 2006

Authors

Affiliations

AMEDEO S. MARRAZZI

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SHARON WOODRUFF

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DENIS KENNEDY

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Professor of Psychiatry and Neuropharmacology and Chief of Neuropharmacology, University of Missouri Institute of Psychiatry, 5400 Arsenal St., St. Louis, Mo. 63139

Acting Chief of Neurology, University of Missouri Institute of Psychiatry, 5400 Arsenal St., St. Louis, Mo. 63139

Research Resident, University of Missouri Institute of Psychiatry, 5400 Arsenal St., St. Louis, Mo. 63139

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Perceptual Challenge to Measure Illness and Therapy

Abstract

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