The Treatment of Depression with a Single Daily Dose of Imipramine Pamoate

J. MENDELS and JOSEPH DIGIACOMOAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 130, Number 9

https://doi.org/10.1176/ajp.130.9.1022

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Abstract

A controlled comparison of the effects of 50 mg. of imipramine hydrochloride given three times daily and 150 mg. of imipramine pamoate in a single bedtime dose revealed no significant difference in either therapeutic effects or side effects in a group of 40 hospitalized depressed patients. The authors note the advantages of a single night dose of antidepressant medication.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 130 • Number 9 • September 1973

Pages: 1022 - 1024

PubMed: 4727758

History

Published in print: September 1973

Published online: 1 April 2006

Authors

Details

J. MENDELS

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JOSEPH DIGIACOMO

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Professor and Chief, Depression Research Unit, University of Pennsylvania, Philadelphia, Pa. and Philadelphia Veterans Administration Hospital, University and Woodland Aves., Philadelphia, Pa. 19104

Associate Professor, Department of Psychiatry, University of Pennsylvania, Philadelphia, Pa. and Philadelphia Veterans Administration Hospital, University and Woodland Aves., Philadelphia, Pa. 1910

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The Treatment of Depression with a Single Daily Dose of Imipramine Pamoate

Abstract

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