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Published Online: March 1942

EXPERIMENTAL "SHOCK THERAPIES" IN CATS WITH INSULIN AND METRAZOL : Histopathologic Study

META A. NEUMANN, ROBERT COHN, and SOLOMON KATZENELBOGENAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 98, Number 5

https://doi.org/10.1176/ajp.98.5.668

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Abstract

The effect of sniffles on the central nervous system is difficult to evaluate. We are also at a loss to explain the peculiar changes of the pulmonary vessels. We were unable to find any references in the literature pertaining to this condition. Congestion and hemorrhages in thoracic and abdominal organs were equally pronounced in both treated and control animals.

It should be emphasized that in every animal brain one could see instances of ischemic homogeneous changes as well as acute pallor, swelling and chromatolysis, often side by side. Cells undergoing cyto-or karyolysis could always be found. Other neurocytes were entirely normal and showed well-stained Nissl substance.

In view of the findings of other workers, Ammon's horn was studied with particular care in every instance. We agree with Winkleman's and Moore's observations that there are no widespread changes in this area subsequent to either insulin or metrazol injections.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 98 • Number 5 • March 1942

Pages: 668 - 672

History

Published in print: March 1942

Published online: 1 April 2006

Authors

Affiliations

META A. NEUMANN

Saint Elizabeths Hospital, Washington, D. C.

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ROBERT COHN

Saint Elizabeths Hospital, Washington, D. C.

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SOLOMON KATZENELBOGEN

Saint Elizabeths Hospital, Washington, D. C.

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EXPERIMENTAL "SHOCK THERAPIES" IN CATS WITH INSULIN AND METRAZOL : Histopathologic Study

Abstract

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