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The Journal of Neuropsychiatry and Clinical Neurosciences

  • Volume 2
  • Number 1
  • February 1990

Publication date: 01 February 1990

Pages1–14

The prevalence, diagnosis, clinical presentation, evolution, and treatment of depression and mania following stroke are discussed. Among the many studies presented in the review is one that indicates major depression following right hemisphere lesions is ...

https://doi.org/10.1176/jnp.2.1.1

Publication date: 01 February 1990

Pages20–27

The relationship of dopamine receptor binding in the caudate nucleus and the putamen to neurological and neuropsychological functioning was examined in 21 patients with Huntington's disease (HD) and eight individuals at risk of developing Huntington's ...

https://doi.org/10.1176/jnp.2.1.20

Publication date: 01 February 1990

Pages28–33

A retrospective chart review was undertaken to assess the prevalence of specifically defined psychiatric symptoms in 217 outpatients with clinically probable Alzheimer's disease. A weak but significant correlation was found between Alzheimer's disease and ...

https://doi.org/10.1176/jnp.2.1.28

Publication date: 01 February 1990

Pages34–43

Most patients with major depression have increased 24-hour urinary free cortisol and cortisol nonsuppression after dexamethasone administration, which are cornerstones of a diagnosis of Cushing's syndrome. Similarly, Cushing's syndrome patients often ...

https://doi.org/10.1176/jnp.2.1.34

Publication date: 01 February 1990

Pages44–52

Over the past several years, research has demonstrated that the excitatory amino acids serve as the major excitatory neurotransmitters in cerebral cortex and hippocampus. Neurons that contain excitatory amino acids play crucial roles in neuropsychological ...

https://doi.org/10.1176/jnp.2.1.44

Publication date: 01 February 1990

Pages53–58

A prolonged (interictal) but reversible delirium was induced by electroconvulsive therapy (ECT) in 10 of 87 (11%) elderly depressed patients. Brain magnetic resonance imaging (MRI) revealed several structural abnormalities, particularly basal ganglia and ...

https://doi.org/10.1176/jnp.2.1.53

Publication date: 01 February 1990

Pages59–63

Unlike patients with irreversible dementia, elderly depressed patients with cognitive impairment are thought to have relatively preserved recognition, memory, and language abilities. To test this hypothesis, the authors compared memory and naming ...

https://doi.org/10.1176/jnp.2.1.59

Publication date: 01 February 1990

Pages64–66

In clinical practice, distinguishing drug-induced parkinsonism from Parkinson's disease may be difficult. Asymmetry is generally not felt to be common in drug-induced parkinsonism. The authors investigated asymmetry of signs and symptoms in 20 patients ...

https://doi.org/10.1176/jnp.2.1.64

Publication date: 01 February 1990

Pages66–69

Nine patients with mild Tourette's syndrome completed a cross-over, placebo-controlled study of clonidine administered transdermally. Although the subjects showed no improvement on objective measures of symptom severity, most subjects felt they had ...

https://doi.org/10.1176/jnp.2.1.66

Publication date: 01 February 1990

Pages69–71

A review of the phenomena involved in reflex epilepsy illustrates that ideas have a neural substrate. The ideational substratum and, at times, associative links to other stimuli have physiological (epileptogenic) power. These phenomena can be applied to ...

https://doi.org/10.1176/jnp.2.1.69

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