The Journal of Neuropsychiatry and Clinical Neurosciences
- Volume 7
- Number 2
- May 1995
Publication date: 01 May 1995
Pages125–134Encephalitis lethargica (von Economo's encephalitis), pandemic from 1917 to 1926, opened a window on the study of behavioral consequences of infection-induced subcortical disorder. Widely varying acute manifestations included extrapyramidal disorders, ...
https://doi.org/10.1176/jnp.7.2.125Publication date: 01 May 1995
Pages135–144Two primary hypotheses have been proposed to explain the pathophysiology of the neuroleptic malignant syndrome (NMS): 1) that NMS is produced by abrupt and extensive central dopamine receptor blockade by neuroleptics, particularly in nigrostriatal and ...
https://doi.org/10.1176/jnp.7.2.135Publication date: 01 May 1995
Pages145–154In a retrospective case review of 336 outpatients who underwent neuropsychiatric evaluations, patients were sorted into five groups: 1) atypical psychiatric; 2) atypical neurological; 3) prior psychiatric/new-onset neurological; 4) prior neurological/new-...
https://doi.org/10.1176/jnp.7.2.145Publication date: 01 May 1995
Pages155–168This study compares two of the most widely used statistical techniques for analyzing data obtained from [15O]H2O PET studies of brain function. The Friston method (SPM94) and the Worsley (Montreal) method were applied to a single data set of 33 subjects ...
https://doi.org/10.1176/jnp.7.2.155Publication date: 01 May 1995
Pages169–175Auditory probe evoked potential attenuation was measured as an index of hemispheric activity in 10 subjects with a history of childhood trauma and 10 matched subjects without such history while they recalled a neutral memory and then a traumatic memory. ...
https://doi.org/10.1176/jnp.7.2.169Publication date: 01 May 1995
Pages176–179Clinicians have long associated Parkinson's disease (PD) with personality traits such as seriousness and industriousness. In previous studies, patients with PD scored lower than matched orthopedic control subjects on novelty seeking, which is thought to ...
https://doi.org/10.1176/jnp.7.2.176Publication date: 01 May 1995
Pages180–187The authors examined change in cerebral metabolic function over time by using PET in HIV-infected individuals diagnosed with AIDS. Ten subjects with AIDS received [18F]2-fluoro-2-deoxy-D-glucose PET scans and completed a comprehensive neuropsychological ...
https://doi.org/10.1176/jnp.7.2.180Publication date: 01 May 1995
Pages188–196To evaluate the pathophysiology of frontal lobe dementia (FLD), the authors compared regional cerebral blood flow (rCBF) in matched groups of FLD, probable Alzheimer's disease (AD), and major depression patients and normal control subjects (n = 7 each). ...
https://doi.org/10.1176/jnp.7.2.188Publication date: 01 May 1995
Pages197–206Increasing evidence suggests that smooth pursuit eye movement (SPEM) dysfunction may serve as an endophenotype or genetic marker of schizophrenia. The authors tested SPEM and visual fixation (VF) in 31 patients with schizophrenia, 33 of their first-degree ...
https://doi.org/10.1176/jnp.7.2.197Publication date: 01 May 1995
Pages207–212This study characterized memory functions in geriatric schizophrenic inpatients with a battery of memory tests sensitive to neuropsychological impairments in either temporal or frontal brain regions. In patients clinically rated as cognitively impaired (n ...
https://doi.org/10.1176/jnp.7.2.207Publication date: 01 May 1995
Pages213–217This pilot study examined and quantified rotational asymmetry (the tendency to turn preferentially to the right or left side). An automated device was used to measure turning (circling) in 9 children with autism and 27 normal control subjects and ...
https://doi.org/10.1176/jnp.7.2.213Publication date: 01 May 1995
Pages218–222The authors examined 21 outpatients with obsessive-compulsive disorder for five neurological soft signs and abnormalities on two neuropsychological tests before and after 10 to 12 weeks of treatment with serotonin reuptake inhibitors. Patients showed a ...
https://doi.org/10.1176/jnp.7.2.218Publication date: 01 May 1995
Pages223–229Respiratory dyskinesia is a common but under-recognized side effect of chronic neuroleptic administration. It manifests as irregular respiration, dyspnea, grunting or gasping, and abnormal chest or esophageal movements. It occurs almost exclusively in ...
https://doi.org/10.1176/jnp.7.2.223Publication date: 01 May 1995
Pages230–234The outcome of all psychosurgical operations (stereotactic subcaudate tractotomies) performed at the Geoffrey Knight National Unit for Affective Disorders in London since 1979 is reviewed. Of patients who had suffered severe mood or obsessive-compulsive ...
https://doi.org/10.1176/jnp.7.2.230Publication date: 01 May 1995
Pages235–237Temporal lobe epilepsy may present with features similar to those of psychiatric disorders, making diagnosis difficult, especially in an elderly population. The authors present two cases illustrating key points leading to proper diagnosis and treatment.
https://doi.org/10.1176/jnp.7.2.235Publication date: 01 May 1995
Pages237–239A patient who presented with seizures, opisthotonos, catatonia, and autonomic dysfunction developed features consistent with sporadic encephalitis lethargica. She received a course of ECT and had full recovery.
https://doi.org/10.1176/jnp.7.2.237Publication date: 01 May 1995
Pages239–242Two cases of Gerstmann-Straussler-Scheinker syndrome (GSS) are discussed in detail. These cases illustrate the variable clinical course and mostly cortical features of GSS-associated dementia. Given the availability of genetic tests that can now diagnose ...
https://doi.org/10.1176/jnp.7.2.239Article
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