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Published Online: May 1959

CYLOSERINE AS AN ANTIDEPRESSANT AGENT

Publication: American Journal of Psychiatry

Abstract

Cycloserine appears to be a psychopharmacological agent in that 1. It reverses depressions to normal or hyperactive mood and at the same time causes subtle changes in behavior; 2. It may aggravate mental disorders; and 3. It seems to potentiate Marsilid. Cycloserine may become a valuable tool in psychopharmacological research and may also find therapeutic use in depressions, provided the initial dose does not exceed 500 mg. a day and potentially psychotic patients receive more than average supervision.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 1025 - 1026
PubMed: 13637281

History

Published in print: May 1959
Published online: 1 April 2006

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GEORGE E. CRANE
The Divisions of Neuropsychiatry and of Pulmonary Diseases, Montefiore Hosp., The Bronx, N. Y.

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