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Published Online: December 1962

PLASMA IMIPRAMINE LEVEL IN SYNDROMES OF DEPRESSION

Publication: American Journal of Psychiatry

Abstract

Imipramine plasma level was determined after a single oral dose. Patients who responded to subsequent imipramine therapy showed low plasma levels, refractory cases showed high levels. The low plasma levels of responders continued during therapy. Their imipramine stool and urine excretions were also low. A differential binding of the drug according to psychopathology was discussed.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 574 - 575
PubMed: 13963558

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Published in print: December 1962
Published online: 1 April 2006

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Creedmoor Institute for Psychobiologic Studies, Queens Village, N. Y.
Geigy Research Laboratories, Yonkers, N. Y.

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