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Chapter 22.Benzodiazepines

Edited by:
https://doi.org/10.1176/appi.books.9781615371624.as22

Sections

History and Discovery | Structure–Activity Relations | Pharmacokinetics and Disposition | Mechanism of Action | Therapeutic Uses | Side Effects and Toxicology | Drug–Drug Interactions | Clinical Issues | Medicolegal Issues | Conclusion | References

Excerpt

In spite of adverse publicity and a problematic public image, the most widely prescribed psychiatric medication in the United States over the past two decades is not an antidepressant, an atypical antipsychotic, or a mood stabilizer, but the benzodiazepine alprazolam, with more than 48 million prescriptions issued in 2013 (see Grohol 2015; Stahl 2002).

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