A Rational Framework for the Development, Evaluation, and Use of Psychoactive Drugs

SAMUEL IRWINAuthors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 124, Number 8S

https://doi.org/10.1176/ajp.124.8S.1

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Abstract

The author attempts to construct a model for patient assessment and psychiatric drug therapy akin to that of somatic therapy. It is suggested that drug effects on major target functions of behavior can form a basis for their rational selection and use and attention is drawn to their actions of probable therapeutic significance. Rejected as relatively unsatisfactory is the present tendency to select drugs on the basis of their presumed effects on diagnostic entities.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 124 • Number 8S • February 1968

Pages: 1 - 19

PubMed: 4865729

History

Published in print: February 1968

Published online: 1 April 2006

Authors

Details

SAMUEL IRWIN

Professor of pharmacology in the department of psychiatry, University of Oregon Medical School, 3181 S.W. Sam Jackson Park Road, Portland, Ore. 97201, and is also with the Oregon Regional Primate Research Center, Beaverton, Ore

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A Rational Framework for the Development, Evaluation, and Use of Psychoactive Drugs

Abstract

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