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Research Article
Published Online: November 1990

Influence of patient-related variables on clozapine plasma levels

Publication: American Journal of Psychiatry

Abstract

The authors investigated the clozapine plasma levels of 148 psychiatric inpatients. Multiple regression analysis revealed a linear relationship between dose of clozapine and plasma concentrations. The analysis showed a significant influence of dose, sex, smoking, weight, and age on the plasma concentrations of clozapine under clinical conditions. These results remained significant when clozapine doses below 150 mg/day and above 500 mg/day were excluded from the analysis.

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Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 1471 - 1475
PubMed: 2221158

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Published in print: November 1990
Published online: 1 April 2006

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