Chlordiazepoxide and Hostility in Anxious Outpatients

Karl Rickels, M.D., and Robert W. Downing, PH.D.Authors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 131, Number 4

https://doi.org/10.1176/ajp.1974.131.4.442

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Abstract

Chlordiazepoxide proved significantly better than placebo in reducing hostile, irritable, and anxious symptomatology in 225 anxious neurotic outpatients. The findings reported here failed to confirm the increases in hostility believed to be induced by chlordiazepoxide observed by others. The authors see little justification for avoiding use of chlordiazepoxide by anxious outpatients with concomitant hostility and irritability.

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 131 • Number 4 • April 1974

Pages: 442 - 444

PubMed: 4592554

History

Published in print: April 1974

Published online: 24 April 2020

Authors

Affiliations

Karl Rickels, M.D.

Dr. Rickels is Professor of Psychiatry and Pharmacology, University of Pennsylvania, 203 Piersol Building, University Hospital, 3400 Spruce St., Philadelphia, Pa. 19104, and Director of Psychopharmacology, Philadelphia General Hospital. Dr. Downing is Associate Professor of Psychology in Psychiatry, University of Pennsylvania, and Chief, Psychology Service, University of Pennsylvania Division Psychiatric Service, Philadelphia General Hospital, Philadelphia, Pa.

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Robert W. Downing, PH.D.

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Chlordiazepoxide and Hostility in Anxious Outpatients

Abstract

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