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Published Online: 1 January 2013

Complex Challenges in Treating Depression During Pregnancy

Abstract

The treatment of depression during pregnancy can be challenging for patients and providers alike. An increasing attention to perinatal mood disorders has led to an expanding literature that is often difficult for providers to navigate. It can be a challenge for providers to feel comfortable reviewing the broad scope of the risks and benefits of treatments in the context of the limitations of the literature. Women who are depressed during pregnancy have been found to have an elevated risk of poor obstetrical outcomes, although studies of the relationship between depression and outcomes are limited. Women who are treated with antidepressants during pregnancy are also at risk for a host of poor obstetrical and fetal outcomes. The risks for these outcomes are often confused by confounding factors and study design limitations. Understanding the current data and their limitations will allow providers to guide their patients in choosing treatment options. Consistent and simple strategies should be used when discussing the risk-benefit analysis with the patient.

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Information

Published In

Go to American Journal of Psychiatry
Go to American Journal of Psychiatry
American Journal of Psychiatry
Pages: 12 - 20
PubMed: 23288385

History

Received: 4 April 2012
Revision received: 27 June 2012
Accepted: 16 July 2012
Published online: 1 January 2013
Published in print: January 2013

Authors

Details

Linda H. Chaudron, M.D., M.S.
From the Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, N.Y.

Notes

Address correspondence to Dr. Chaudron ([email protected]).

Funding Information

Dr. Chaudron reports no financial relationships with commercial interests.

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