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Published Online: 31 March 2015

Association of a Brain Methylation Site With Clinical Outcomes in Depression Does Not Replicate Across Populations

Rudolf Uher, M.D., Ph.D., Stephan Ripke, M.D., Ph.D., Bertram Müller-Myhsok, M.D., Cathryn M. Lewis, Ph.D., and Roy H. Perlis, M.D.Authors Info & Affiliations

Publication: American Journal of Psychiatry

Volume 172, Number 4

https://doi.org/10.1176/appi.ajp.2015.14101348

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Information & Authors

Information

Published In

American Journal of Psychiatry

Volume 172 • Number 4 • April 01, 2015

Pages: 395 - 397

PubMed: 25827039

History

Accepted: January 2015

Published online: 31 March 2015

Published in print: April 01, 2015

Authors

Affiliations

Rudolf Uher, M.D., Ph.D.

From the Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada; King's College London, Institute of Psychiatry, Psychology & Neuroscience, MRC Social, Genetic and Developmental Psychiatry Centre, London; Broad Institute, Cambridge, Mass.; Massachusetts General Hospital, Boston; Institute of Translational Medicine, University of Liverpool, United Kingdom; Max Planck Institute of Psychiatry, Munich, Germany; and Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

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Stephan Ripke, M.D., Ph.D.

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Bertram Müller-Myhsok, M.D.

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Cathryn M. Lewis, Ph.D.

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Roy H. Perlis, M.D.

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Competing Interests

Dr. Müller-Myhsok is a consultant with HMNC and an inventor on several patents in the subject area of pharmacogenetics. Dr. Lewis has received consultant fees from Eli Lilly. Dr. Perlis has served on scientific advisory boards or received consulting fees from Genomind LLC, Healthrageous, Perfect Health, Pfizer, Proteus Biomedical, Psybrain, and RID Ventures, and he receives royalties through Massachusetts General Hospital from Concordant Rater Systems (now UBC). Drs. Uher and Ripke report no financial relationships with commercial interests.

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Association of a Brain Methylation Site With Clinical Outcomes in Depression Does Not Replicate Across Populations

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